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Alnylam Collaborated with Roche to Co-Develop and Co-Commercialize Zilebesiran for Hypertension in Patients with High Cardiovascular Risk

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Alnylam Collaborated with Roche to Co-Develop and Co-Commercialize Zilebesiran for Hypertension in Patients with High Cardiovascular Risk

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  • Alnylam will receive $310M up front, additional near-term fees incl. development milestones over the next few years, regulatory & sales milestones for ~$2.8B along with royalties on net sales of zilebesiran outside the US as well as an equal share of profits & losses in the US
  • Alnylam to get an equal profit share in the US & will lead a joint clinical development plan for 1st indication with Roche’s participation incl. cardiovascular outcomes trial with development costs shared 40% by Alnylam & 60% by Roche
  • Roche will get an exclusive right to commercialize zilebesiran outside the US & may lead development for additional indications in the future. The collaboration will combine Alnylam’s leadership in RNAi therapeutics with Roche’s global commercial reach to develop & launch innovative therapies globally for sev. cardiovascular diseases

Ref: Businesswire | Image: Alnylam

Related News:- Alnylam Reports Updated Interim Results from the P-I Study of ALN-APP for Alzheimer’s Disease and Cerebral Amyloid Angiopathy

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Senior Editor

Neha is a Senior Editor at PharmaShots. She is passionate and very enthusiastic about recent updates and developments in the life sciences and pharma industry. She covers Biopharma, MedTech, and Digital health segments along with different reports at PharmaShots. She can be contacted at connect@pharmashots.com.

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